University of Bayreuth, Press Release Nr. 066/2022 - 4 May 2022
Gene expression in the nervous system: Bayreuth researchers discover a mechanism for its targeted stimulation
Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence on the exact time at which genes are read and on the intensity with which this happens. In their recent Nature Communications article, researchers from the University of Bayreuth have shown exactly how RNA polymerase II is activated in nerve cells, and how this stimulates gene expression, the targeted use of genetic information. Their discoveries contain valuable starting points for further biomedical research.
Dr. Vladyslava Gorbovytska, first author of the study, isolates RNA polymerase II from pig thymus.
UBT / Chr. Wißler.
Dr. Vladyslava Gorbovytska purifies the macromolecular complexes that were necessary for the successful completion of the study.
UBT / Chr. Wißler.
Participants in the study at the University of Bayreuth were: Filiz Kuybu, Andreas Pittroff, Theresia Brennecke and Dr. Vladyslava Gorbovytska (from left to right).
Fabienne Lindner.