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Prof. Dr. Ruth Freitag

Prof. Dr. Ruth Freitag

Fakultät für Angewandte Naturwissenschaften
Lehrstuhl für Bioprozesstechnik


Berufserfahrung

seit 2003

Professorin, Lehrstuhl für Bioprozesstechnik, Ingenieurwissenschaftliche Fakultät, Universität Bayreuth


2002Director of the Institute of Chemical and Biological Process science (ISP) in the Faculty of Basic Science, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland
05/1996 – 12/2005Assistant / Associate Professor for Chemical Biotechnology, Department of Chemistry, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland
06/1995 – 05/1996

Privatdozentin, Technische Chemie/Biotechnologie,
Universität Hannover



Ausbildung

07/1991 – 05/1995

Habilitation, Technische Chemie/Biotechnologie,
Universität Hannover


03/1990 – 06/1991

PostDoc, Yale University, Department of Chemical Engineering, Prof. Csaba Horvath, New Haven, CT, USA


10/1987 – 02/1990

Promotion, Technische Chemie/Biotechnologie, Universität Hannover


1987Diplom: Chemie, Universität Hannover, Diplomarbeit: Prof. Karl Schügerl

Auszeichnungen und andere Verantwortlichkeiten

seit 2012Mitglied des Forschungsbeirates zum Fraunhofer Systemforschungsprojekt „Zellfreie Bioproduktion“
seit 2008Mitglied (Expertin) der ASIIN, Akkreditierungsorganisation für Bachelor- und Master-Studiengänge in den Bereichen Informatik, Mathematik, Ingenieur- und Naturwissenschaften
seit 2004Mitglied im Bayreuther Zentrum für Molekulare Biowissenschaften (BZMB), Zuordnung zur kollegialen Leitung
seit 2003Mitglied der vom Bundesrat gewählten Eidgenössischen Kommission für Technologie und Innovation (KTI) im Eidgenössischen Volkswirtschaftsdepartement, Bern, Schweiz


Fakultät für Angewandte Naturwissenschaften
Lehrstuhl für Bioprozesstechnik


Ausgewählte Publikationen

2017

Raup, Alexander; Wang, Hui; Synatschke, Christopher V.; Jérôme, Valérie; Agarwal, Seema; Pergushov, Dmitry V.; Müller, Axel H. E.; Freitag, Ruth
Compaction and transmembrane delivery of pDNA : differences between l-PEI and two types of amph ...
In: Biomacromolecules Bd. 18 (2017) Heft 3. - S. 808-818
doi:10.1021/acs.biomac.6b01678 ...

Jérôme, Valérie; Thoring, Lena; Salzig, Denise; Kubick, Stefan; Freitag, Ruth
Comparison of cell-based vs. cell-free mammalian systems for the production of a recombinant hu ...
In: Engineering in Life Sciences (2017)
doi:10.1002/elsc.201700005 ...

Jérôme, Valérie; Werner, Melanie; Kaiser, Patrick; Freitag, Ruth
Creating a Biomimetic Microenvironment for the Ex Vivo Expansion of Primary Human T Lymphocytes
In: Macromolecular Bioscience (2017)
doi:10.1002/mabi.201700091 ...

Kaiser, Patrick; Reich, Steffen; Leykam, Daniel; Willert-Porada, Monika; Greiner, Andreas; Freitag, Ruth
Electrogenic Single-Species Biocomposites as Anodes for Microbial Fuel Cells
In: Macromolecular Bioscience (2017)
doi:10.1002/mabi.201600442 ...

Stahlschmidt, Ullrich; Jérôme, Valérie; Majewski, Alexander P.; Müller, Axel H. E.; Freitag, Ruth
Systematic Study of a Library of PDMAEMA-Based, Superparamagnetic Nano-Stars for the Transfecti ...
In: Polymers Bd. 9 (2017) Heft 5
doi:10.3390/polym9050156 ...

2016

Weithmann, Nicolas; Weig, Alfons; Freitag, Ruth
Process parameters and changes in the microbial community patterns during the first 240 days of ...
In: AMB Express Bd. 6 (2016) Heft 1
doi:10.1186/s13568-016-0219-7 ...

Raup, Alexander; Stahlschmidt, Ullrich; Jérôme, Valérie; Synatschke, Christopher V.; Müller, Axel H. E.; Freitag, Ruth
Influence of Polyplex Formation on the Performance of Star-Shaped Polycationic Transfection Agen ...
In: Polymers Bd. 8 (2016) Heft 6. - S. 224
doi:10.3390/polym8060224 ...

Raup, Alexander; Jérôme, Valérie; Freitag, Ruth; Synatschke, Christopher V.; Müller, Axel H. E.
Promoter, transgene, and cell line effects in the transfection of mammalian cells using PDMAEMA ...
In: Biotechnology Reports Bd. 11 (2016) . - S. 53-61
doi:10.1016/j.btre.2016.05.003 ...

Zambrano, Kenny; Jérôme, Valérie; Freitag, Ruth; Buchholz, Rainer; Jäck, Hans-Martin; Hübner, Holger; Schuh, Wolfgang
Prolonged Ex vivo expansion and differentiation of naïve murine CD43− B splenocytes
In: Biotechnology Progress Bd. 32 (2016) Heft 4. - S. 978-989
doi:10.1002/btpr.2265 ...

2015

Pineda Contreras, Paul; Kuttner, Christian; Fery, Andreas; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Renaissance for Low Shrinking Resins : all-in-one Solution by Bi-Functional Vinylcyclopropane-A ...
In: Chemical Communications Bd. 51 (2015) Heft 59. - S. 11899-11902
doi:10.1039/C5CC03901K ...

Shi, Yinfeng; Zhou, Peiran; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Enzymatically Degradable Polyester-Based Adhesives
In: ACS Biomaterials Science & Engineering (2015)
doi:10.1021/acsbiomaterials.5b00217 ...

Werner, Melanie; Schmoldt, Daria; Hilbrig, Frank; Jérôme, Valérie; Raup, Alexander; Zambrano, Kenny; Hübner, Holger; Buchholz, Rainer; Freitag, Ruth
High Cell Density Cultivation of Human Leukemia T Cells (Jurkat Cells) in Semipermeable Polyele ...
In: Engineering in Life Sciences Bd. 15 (2015) Heft 4. - S. 357-367
doi:10.1002/elsc.201400186 ...

Käfer, Florian; Liu, Fangyao; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Karg, Matthias; Agarwal, Seema
LCST and UCST in one : Double thermoresponsive behavior of block copolymers of poly(ethylene gl ...
In: Langmuir Bd. 31 (2015) Heft 32. - S. 8940-8946
doi:10.1021/acs.langmuir.5b02006 ...

Knierim, Christian; Enzeroth, Michaela; Kaiser, Patrick; Dams, Christian; Nette, David; Seubert, Andreas; Klingl, Andreas; Greenblatt, Charles L.; Jérôme, Valérie; Agarwal, Seema; Freitag, Ruth; Greiner, Andreas
Living Composites of Bacteria and Polymers as Biomimetic Films for Metal Sequestration and Bior ...
In: Macromolecular Bioscience Bd. 15 (2015) Heft 8. - S. 1052-1059
doi:10.1002/mabi.201400538 ...

Duan, Gaigai; Jiang, Shaohua; Jérôme, Valérie; Wendorff, Joachim H.; Fathi, Amir; Uhm, Jacqueline S.; Altstädt, Volker; Herling, Markus; Breu, Josef; Freitag, Ruth; Agarwal, Seema; Greiner, Andreas
Ultralight, Soft Polymer Sponges by Self-Assembly of Short Electrospun Fibers in Colloidal Disp ...
In: Advanced Functional Materials Bd. 25 (2015) Heft 19. - S. 2850-2856
doi:10.1002/adfm.201500001 ...

2014

Kaiser, Patrick; Werner, Melanie; Jérôme, Valérie; Hübner, Holger; Buchholz, Rainer; Freitag, Ruth
Cell Retention by Encapsulation for the Cultivation of Jurkat Cells in Fixed and Fluidized Bed ...
In: Biotechnology and Bioengineering Bd. 111 (2014) Heft 12. - S. 2571-2579
doi:10.1002/bit.25304 ...

Freitag, Ruth
Chromatographic techniques in the downstream processing of proteins in biotechnology
Animal cell biotechnology : methods and protocols
New York, NY : Humana Press, 2014. - S. 419-458 . - (Methods in Molecular Biology; 1104)
doi:10.1007/978-1-62703-733-4_25 ...

Wang, Hui; Synatschke, Christopher V.; Raup, Alexander; Jérôme, Valérie; Freitag, Ruth; Agarwal, Seema
Oligomeric dual functional antibacterial polycaprolactone
In: Polymer Chemistry Bd. 5 (2014) Heft 7. - S. 2453-2460
doi:10.1039/C3PY01467C ...

2013

Majewski, Alexander P.; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
PDMAEMA-Grafted Core-Shell-Corona Particles for Nonviral Gene Delivery and Magnetic Cell Separa ...
In: Biomacromolecules Bd. 14 (2013) Heft 9. - S. 3081-3090
doi:10.1021/bm400703d ...

Majewski, Alexander P.; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
PDMAEMA-Grafted Core–Shell–Corona Particles for Nonviral Gene Delivery and Magnetic Cell Separa ...
In: Biomacromolecules Bd. 14 (2013) Heft 9. - S. 3081-3090
doi:10.1021/bm400703d ...

Werner, Melanie; Biss, Karsten; Jérôme, Valérie; Hilbrig, Frank; Freitag, Ruth; Zambrano, Kenny; Hübner, Holger; Buchholz, Rainer; Mahou, Redouan; Wandrey, Christine
Use of the mitochondria toxicity assay for quantifying the viable cell density of microencapsul ...
In: Biotechnology Progress Bd. 29 (2013) Heft 4. - S. 986-993
doi:10.1002/btpr.1734 ...

2012

Freimark, Denise; Jérôme, Valérie; Freitag, Ruth
Effect of process parameters and product-host-interaction on hVEGFA-production by recombinant C ...
In: Biotechnology Progress Bd. 28 (2012) Heft 3. - S. 762-772
doi:10.1002/btpr.1524 ...

Majewski, Alexander P.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
Dual-responsive magnetic core-shell nanoparticles for non-viral gene delivery and cell separati ...
In: Abstracts of Papers of the American Chemical Society Bd. 243 (2012) . - S. 40-POLY
Symposium on Ionic Liquids - Science and Applications / 243rd National Spring Meeting of the American-Chemical-Society, San Diego, CA, MAR 25-29, 2012, San Diego, CA,

Majewski, Alexander P.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
Dual-Responsive Magnetic Core-Shell Nanoparticles for Nonviral Gene Delivery and Cell Separatio ...
In: Biomacromolecules Bd. 13 (2012) Heft 3. - S. 857-866
doi:10.1021/bm2017756 ...

Hilbrig, Frank; Freitag, Ruth
Isolation and purification of recombinant proteins, antibodies and plasmid DNA with hydroxyapat ...
In: Biotechnology Journal Bd. 7 (2012) Heft 1. - S. 90-102
doi:10.1002/biot.201100015 ...

Majewski, Alexander P.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.; Schmalz, Holger
Dual-Responsive Magnetic Core–Shell Nanoparticles for Nonviral Gene Delivery and Cell Separatio ...
In: Biomacromolecules Bd. 13 (2012) Heft 3. - S. 857-866
doi:10.1021/bm2017756 ...

Schallon, Anja; Synatschke, Christopher V.; Jérôme, Valérie; Müller, Axel H. E.; Freitag, Ruth
Nanoparticulate Nonviral Agent for the Effective Delivery of pDNA and siRNA to Differentiated C ...
In: Biomacromolecules Bd. 13 (2012) Heft 11. - S. 3463-3474
doi:10.1021/bm3012055 ...

2011

Pfaff, André; Schallon, Anja; Ruhland, Thomas M.; Majewski, Alexander P.; Schmalz, Holger; Freitag, Ruth; Müller, Axel H. E.
Magnetic and Fluorescent Glycopolymer Hybrid Nanoparticles for Intranuclear Optical Imaging
In: Biomacromolecules Bd. 12 (2011) Heft 10. - S. 3805-3811
doi:10.1021/bm201051p ...

Arnold, Marc; Bittermann, Holger; Kalbfuss-Zimmermann, Bernd; Neumann, Thomas; Schmidt, Kristina; Sekul, Renate; Hilbrig, Frank; Ludolph, Heiko; Freitag, Ruth
Antibody purification by affinity chromatography based on small molecule affinity ligands ident ...
In: Journal of Chromatography A Bd. 1218 (2011) Heft 29. - S. 4649 - 4659
doi:10.1016/j.chroma.2011.05.040 ...

Schallon, Anja; Synatschke, Christopher V.; Pergushov, Dmitry V.; Jérôme, Valérie; Müller, Axel H. E.; Freitag, Ruth
DNA Melting Temperature Assay for Assessing the Stability of DNA Polyplexes Intended for Nonvir ...
In: Langmuir Bd. 27 (2011) Heft 19. - S. 12042-12051
doi:10.1021/la201803c ...

Synatschke, Christopher V.; Schallon, Anja; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H. E.
Influence of Polymer Architecture and Molecular Weight of Poly(2-(dimethylamino)ethyl methacryl ...
In: Biomacromolecules Bd. 12 (2011) Heft 12. - S. 4247-4255
doi:10.1021/bm201111d ...

Pfaff, André; Schallon, Anja; Ruhland, Thomas M.; Majewski, Alexander P.; Schmalz, Holger; Freitag, Ruth; Müller, Axel H. E.
Magnetic and Fluorescent Glycopolymer Hybrid Nanoparticles for Intranuclear Optical Imaging
In: Biomacromolecules Bd. 12 (2011) Heft 10. - S. 3805-3811
doi:10.1021/bm201051p ...

2010

Freimark, Denise; Jérôme, Valérie; Freitag, Ruth
A GFP-based method facilitates clonal selection of transfected CHO cells
In: Biotechnology Journal Bd. 5 (2010) Heft 1. - S. 24-31
doi:10.1002/biot.200800264 ...

Müllner, Markus; Schallon, Anja; Walther, Andreas; Freitag, Ruth; Müller, Axel H. E.
Clickable, Biocompatible, and Fluorescent Hybrid Nanoparticles for Intracellular Delivery and O ...
In: Biomacromolecules Bd. 11 (2010) Heft 2. - S. 390-396
doi:10.1021/bm901099p ...

2009

Jérôme, Valérie; Heider, Andreas; Schallon, Anja; Freitag, Ruth
Exhaustive in vivo labelling of plasmid DNA with BrdU for intracellular detection in non-viral ...
In: Biotechnology Journal Bd. 4 (2009) Heft 10. - S. 1479-1487
doi:10.1002/biot.200900053 ...

Schubert, Sven; Freitag, Ruth
Investigation of the interaction mechanism of the recombinant human antibody MDJ8 and its fragm ...
In: Journal of Chromatography A Bd. 1216 (2009) Heft 18. - S. 3831 - 3840
doi:10.1016/j.chroma.2009.02.074 ...

Parisot, Judicaël; Kurz, Katrin; Hilbrig, Frank; Freitag, Ruth
Use of azobenzene amino acids as photo-responsive conformational switches to regulate antibody– ...
In: Journal of Separation Science Bd. 32 (2009) Heft 10. - S. 1613-1624
doi:10.1002/jssc.200800698 ...

Hilbrig, Frank; Jérôme, Valérie; Salzig, Mark; Freitag, Ruth
Strategy for the isolation of native dehydrogenases with potential for biosensor development fr ...
In: Journal of Chromatography A Bd. 1216 (2009) Heft 16. - S. 3518 - 3525
doi:10.1016/j.chroma.2008.09.020 ...

Hofstetter, Eugen-Maria; Gabler, Ralf; Peiffer, Stefan; Hilbrig, Frank; Freitag, Ruth
Ammoniakstrippung an einer etablierten, thermophilen Biogasanlage - technische und wirtschaftli ...
In: Chemie Ingenieur Technik Bd. 81 (2009) Heft 7. - S. 921-932
doi:10.1002/cite.200900033 ...

Weiss, Agnes; Jérôme, Valérie; Burghardt, Diana; Likke, Likke; Peiffer, Stefan; Hofstetter, Eugen-Maria; Gabler, Ralf; Freitag, Ruth
Investigation of factors influencing biogas production in a large-scale thermophilic municipal ...
In: Applied Microbiology and Biotechnology Bd. 84 (2009) Heft 5. - S. 987-1001
doi:10.1007/s00253-009-2093-6 ...

2008

Weiss, Agnes; Jérôme, Valérie; Freitag, Ruth; Mayer, Helmut K.
Diversity of the resident microbiota in a thermophilic municipal biogas plant
In: Applied Microbiology and Biotechnology Bd. 81 (2008) Heft 1. - S. 163-173
doi:10.1007/s00253-008-1717-6 ...

Stocker, Gisela; Dumoulin, Dorothée; Vandevyver, Caroline; Hilbrig, Frank; Freitag, Ruth
Screening of a human antibody phage display library against a peptide antigen using stimuli-res ...
In: Biotechnology Progress Bd. 24 (2008) Heft 6. - S. 1314-1324
doi:10.1002/btpr.60 ...

Stocker-Majd, Gisela; Hilbrig, Frank; Freitag, Ruth
Extraction of haemoglobin from human blood by affinity precipitation using a haptoglobin-based ...
In: Journal of Chromatography A Bd. 1194 (2008) Heft 1. - S. 57 - 65
doi:10.1016/j.chroma.2008.03.091 ...

Achmann, Sabine; Hermann, Markus; Hilbrig, Frank; Jérôme, Valérie; Hämmerle, Martin; Freitag, Ruth; Moos, Ralf
Direct detection of formaldehyde in air by a Novel NAD⁺- and glutathione-independent formaldehy ...
In: Talanta Bd. 75 (2008) Heft 3. - S. 786-791
doi:10.1016/j.talanta.2007.12.015 ...

Freitag, Ruth; Hilbrig, Frank
Use of the avidin (imino)biotin system as a general approach to affinity precipitation
Avidin-Biotin interactions : methods and applications
Totowa, NJ : Humana Press, 2008. - S. 35-50 . - (Methods in Molecular Biology; 418)

2007

Jérôme, Valérie; Hermann, Markus; Hilbrig, Frank; Freitag, Ruth
Development of a fed-batch process for the production of a dye-linked formaldehyde dehydrogenas ...
In: Applied Microbiology and Biotechnology Bd. 77 (2007) Heft 4. - S. 779-788
doi:10.1007/s00253-007-1218-z ...

Vandevyver, Caroline; Canarelli, Stéphane; Bossen, Claudia; Fisch, Igor; Motmans, Kris; Raus, Jef; Freitag, Ruth
Investigation and molecular mimicry of the antigen involved in the interaction between the mono ...
In: Biotechnology and Bioengineering Bd. 97 (2007) Heft 4. - S. 721-734
doi:10.1002/bit.21276 ...

Freitag, Ruth; Schumacher, Ivo; Hilbrig, Frank
Affinity precipitation an option for early capture in bioprocessing
In: Biotechnology Journal Bd. 2 (2007) Heft 6. - S. 685-690
doi:10.1002/biot.200600200 ...

Weiss, Agnes; Jérôme, Valérie; Freitag, Ruth
Comparison of strategies for the isolation of PCR-compatible, genomic DNA from a municipal biog ...
In: Journal of Chromatography B Bd. 853 (2007) Heft 1/2. - S. 190 - 197
doi:10.1016/j.jchromb.2007.03.009 ...

Schubert, Sven; Freitag, Ruth
Comparison of ceramic hydroxy- and fluoroapatite versus Protein A/G-based resins in the isolati ...
In: Journal of Chromatography A Bd. 1142 (2007) Heft 1. - S. 106 - 113
doi:10.1016/j.chroma.2006.08.075 ...

Willert-Porada, Monika; Lorenz, Katrin; Freitag, Ruth; Jérôme, Valérie; Pfeiffer, Stefan
Biofilm Based Microbial Fuel Cell
NSTI Nanotech 2007
Boston Mass. : Nano Science and Technology Institute, 2007. - S. 728-731
http://www.nsti.org/publications/Nanotech/2007/pdf ...

O'Mahony, Kevin; Freitag, Ruth; Hilbrig, Frank; Schumacher, Ingo; Müller, Patrick
Integration of bacteria capture via filtration and in situ lysis for recovery of plasmid DNA un ...
In: Biotechnology Progress Bd. 23 (2007) Heft 4. - S. 895-903
doi:10.1021/bp0701113 ...

Achmann, Sabine; Hermann, Markus; Jérôme, Valérie; Hämmerle, Martin; Freitag, Ruth; Moos, Ralf
NAD-unabhängige Formaldehyddehydrogenase aus H. zavarzinii : Einsatz im Biosensor
2007
5. Deutsches Biosensor Symposium 2007, Bochum, Deutschland

Freitag, Ruth; Hilbrig, Frank
Theory and practical understanding of the migration behavior of proteins and peptides in CE and ...
In: Electrophoresis Bd. 28 (2007) Heft 13. - S. 2125-2144
doi:10.1002/elps.200600792 ...

2006

O'Mahony, Kevin; Freitag, Ruth; Dhote, Bernhard; Hilbrig, Frank; Müller, Patrick; Schumacher, Ivo
Capture of Bacteria from Fermentation Broth by Body Feed Filtration : A Solved Problem?
In: Biotechnology Progress Bd. 22 (2006) Heft 2. - S. 471-483
doi:10.1021/bp050302a ...

Pöhner, Claudia; Hilbrig, Frank; Jérôme, Valérie; Freitag, Ruth
Design and Characterization of Stimuli-Responsive FLAG-tag Analogues and the Illumination-Induc ...
In: Biotechnology Progress Bd. 22 (2006) Heft 4. - S. 1170-1178
doi:10.1021/bp060011h ...

Stocker, Gisela; Vandevyver, Caroline; Hilbrig, Frank; Freitag, Ruth
Purification of RT-PCR Competent Poly(A) mRNA from Crude Cell Lysate by Affinity Precipitation
In: Biotechnology Progress Bd. 22 (2006) Heft 6. - S. 1621-1629
doi:10.1021/bp060095u ...

2005

Desponds, Arnaud; Freitag, Ruth
Light-responsive bioconjugates as novel tools for specific capture of biologicals by photoaffin ...
In: Biotechnology and Bioengineering Bd. 91 (2005) Heft 5. - S. 583-591
doi:10.1002/bit.20479 ...

O'Mahony, Kevin; Freitag, Ruth; Hilbrig, Frank; Müller, Patrick; Schumacher, Ivo
Proposal for a better integration of bacterial lysis into the production of plasmid DNA at larg ...
In: Journal of Biotechnology Bd. 119 (2005) Heft 2. - S. 118-132
doi:10.1016/j.jbiotec.2005.03.020 ...

Suarez, Mougli; Haenni, Marisa; Canarelli, Stéphane; Fisch, Florian; Chodanowski, Pierre; Servis, Catherine; Michielin, Olivier; Freitag, Ruth; Moreillon, Philippe; Mermod, Nicolas
Structure-Function Characterization and Optimization of a Plant-Derived Antibacterial Peptide
In: Antimicrobial Agents and Chemotherapy Bd. 49 (2005) Heft 9. - S. 3847-3857
doi:10.1128/AAC.49.9.3847-3857.2005 ...

Jozwik, Magdalena; Kaczmarski, Krzystof; Freitag, Ruth
Investigation of the steric mass action formalism in the simulation of breakthrough curves on a ...
In: Journal of Chromatography A Bd. 1073 (2005) Heft 1/2. - S. 111 - 121
doi:10.1016/j.chroma.2005.01.059 ...

Yamahata, Christophe; Vandevyver, Caroline; Lacharme, Frederic; Izewska, Paulina; Vogel, Horst; Freitag, Ruth; Gijs, Martin A. M.
Pumping of mammalian cells with a nozzle-diffuser micropump
In: Lab on a Chip Bd. 5 (2005) Heft 10. - S. 1083-1088
doi:10.1039/B504468E ...

Szekely, Laszlo; Freitag, Ruth
Study of the electroosmotic flow as a means to propel the mobile phase in capillary electrochro ...
In: Electrophoresis Bd. 26 (2005) Heft 10. - S. 1928-1939
doi:10.1002/elps.200410194 ...

2004

Szucs, Veronika; Freitag, Ruth
Comparison of a three-peptide separation by capillary electrochromatography, voltage-assisted l ...
In: Journal of Chromatography A Bd. 1044 (2004) Heft 1/2. - S. 201 - 210
doi:10.1016/j.chroma.2004.05.103 ...

Malinova, Vesela; Freitag, Ruth; Wandrey, Christine
Adsorption of charged macromolecules on oppositely charged porous column materials
In: Journal of Chromatography A Bd. 1036 (2004) Heft 1. - S. 25 - 32
doi:10.1016/j.chroma.2003.10.087 ...

Freitag, Ruth
Comparison of the chromatographic behavior of monolithic capillary columns in capillary electro ...
In: Journal of Chromatography A Bd. 1033 (2004) Heft 2. - S. 267 - 273
doi:10.1016/j.chroma.2004.01.053 ...

Leiderer, M.; Ponader, Thomas; Schumacher, Matthias; Lauterbach, Anja; Hilgert, Karin; Hermann, Markus; Jérôme, Valérie; Hämmerle, Martin; Moos, Ralf; Freitag, Ruth
Elektrochemischer Enzym-Biosensor zur Detektion von gasförmigem Formaldehyd
2004
DECHEMA/GVC-Jahrestagung 2004, Karlsruhe

Lauterbach, Anja; Leiderer, M.; Ponader, P.; Schumacher, Matthias; Hämmerle, Martin; Moos, Ralf; Hermann, Markus; Jérôme, Valérie; Freitag, Ruth
Untersuchungen einer 'Dye-linked' Formaldehyddehydrogenase aus methylotrophen Bakterien
2004
BioPerspectives 2004, Wiesbaden, Deutschland

Jess, Andreas; Freitag, Ruth
Verfahren und Prozesse - nicht nur vor Gericht
In: Spektrum (2004) Heft 2. - S. 28-31
http://www.neu.uni-bayreuth.de/de/Uni_Bayreuth/Sta ...

2003

Schmidt, Beata; Wandrey, Christine; Freitag, Ruth
Investigation of particle-based and monolithic columns for cation exchange protein displacement ...
In: Journal of Chromatography A Bd. 1018 (2003) Heft 2. - S. 155 - 167
doi:10.1016/S0021-9673(03)01326-8 ...

Hoegger, Daniela; Freitag, Ruth
Investigation of conditions allowing the synthesis of acrylamide-based monolithic microcolumns ...
In: Electrophoresis Bd. 24 (2003) Heft 17. - S. 2958-2972
doi:10.1002/elps.200305522 ...

Hoegger, Daniela; Freitag, Ruth
Investigation of mixed-mode monolithic stationary phases for the analysis of charged amino acid ...
In: Journal of Chromatography A Bd. 1004 (2003) Heft 1/2. - S. 195 - 208
doi:10.1016/S0021-9673(03)00563-6 ...

Hilbrig, Frank; Freitag, Ruth
Continuous annular chromatography
In: Journal of Chromatography B Bd. 790 (2003) Heft 1/2. - S. 1-15
doi:10.1016/S1570-0232(03)00085-0 ...

Hilbrig, Frank; Freitag, Ruth
Protein purification by affinity precipitation
In: Journal of Chromatography B Bd. 790 (2003) Heft 1/2. - S. 79-90
doi:10.1016/S1570-0232(03)00081-3 ...

Costioli, Matteo D.; Fisch, Igor; Garret-Flaudy, Frédéric; Hilbrig, Frank; Freitag, Ruth
DNA purification by triple-helix affinity precipitation
In: Biotechnology and Bioengineering Bd. 81 (2003) Heft 5. - S. 535-545
doi:10.1002/bit.10497 ...

2002

Canarelli, Stéphane; Fisch, Igor; Freitag, Ruth
Hyphenation of multi-dimensional chromatography and mass spectrometry for the at-line-analysis ...
In: Journal of Chromatography B Bd. 775 (2002) Heft 1. - S. 27-35
doi:10.1016/S1570-0232(02)00286-6 ...

Giovannini, Roberto; Freitag, Ruth
Continuous Separation of Multicomponent Protein Mixtures by Annular Displacement Chromatography
In: Biotechnology Progress Bd. 18 (2002) Heft 6. - S. 1324-1331
doi:10.1021/bp010154y ...

2000

Garret-Flaudy, Frédéric; Freitag, Ruth
Use of the avidin (imino)biotin system as a general approach to affinity precipitation
In: Biotechnology and Bioengineering (2000) Heft 3. - S. 223-234
doi:10.1002/1097-0290(2000)71:3<223::AID-BIT1012>3 ...

Fakultät für Angewandte Naturwissenschaften
Lehrstuhl für Bioprozesstechnik


Prof. Dr. Ruth Freitag

Fachgruppe Ingenieurwissenschaften

Universität Bayreuth
Universitätsstraße 30
D-95447 Bayreuth

Telefon: +49 (0)921 / 55-7370
E-Mail: bioprozesstechnik@uni-bayreuth.de
Homepage: Lehrstuhl für Bioprozesstechnik

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